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Peptide record

TPDB66009

AM-2 Tumor-homing Peptides standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB66009
AM-2
Tumor-homing Peptides
Cancer-related peptides
TumorHoPe2.0
standard
No
A 12-aa standard natural tumor-homing peptides peptide sequence curated from TumorHoPe2.0, with an available 3D structural model.
Sequence
SLSLITMLKISR
Physicochemical Analysis
C60H112N16O17S1
ANDCEQGHFPWYV
LS
1361.71
11.49
2
0
6
+2
-0.20
0.900
162.50
Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
4
Residue Composition
number
0
A
1
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
2
I
3
L
1
K
1
M
0
F
0
P
3
S
1
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 2 L: 3 K: 1 M: 1 F: 0 P: 0 S: 3 T: 1 W: 0 Y: 0 V: 0
Chemical Descriptors
12
C60H112N16O17S1
1361.71
11.49
+2
-0.20
0.900
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Tumor cell
Homing
Hepatocellular carcinoma

Source & Reference

TumorHoPe2.0
TumorHoPe2
Enhanced binding to and killing of hepatocellular carcinoma cells in vitro by melittin when linked with a novel targeting peptide screened from phage display
2013
Honglei Zhao et al. J Pept Sci. 2013 Oct 19(10):639-50.

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
HepG2 cells
Phage Display library
Ph.D.-12 phage peptide library
melittin
Additional Detail Fields 3 fields
melittin
HepG2 cells
Ph.D.-12 phage peptide library