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Peptide record

TPDB66007

OVa-t4 Tumor-homing Peptides standard
8 amino acids
Basic Information
3D PDB MODEL
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TPDB66007
OVa-t4
Tumor-homing Peptides
Cancer-related peptides
TumorHoPe2.0
standard
No
A 8-aa standard natural tumor-homing peptides peptide sequence curated from TumorHoPe2.0, with an available 3D structural model.
Sequence
SIITFEKL
Physicochemical Analysis
C45H75N9O13
ARNDCQGHMPWYV
I
950.14
6.94
1
1
4
-0
0.97
0.837
146.25
Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
2
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
1
E
0
Q
0
G
0
H
2
I
1
L
1
K
0
M
1
F
0
P
1
S
1
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 1 Q: 0 G: 0 H: 0 I: 2 L: 1 K: 1 M: 0 F: 1 P: 0 S: 1 T: 1 W: 0 Y: 0 V: 0
Chemical Descriptors
8
C45H75N9O13
950.14
6.94
-0
0.97
0.837
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Homing

Source & Reference

TumorHoPe2.0
TumorHoPe2
The microtubule-depolymerizing agent ansamitocin P3 programs dendritic cells toward enhanced anti-tumor immunity
2014
Martin K et al. Cancer Immunol Immunother.2014 Sep 63(9):925-38

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
Immature mouse DC cell line SP37a3, Murine tumor cell line EG-7, 3ll-thy1.1-OVa cells
C57Bl/6 mice, Ot-II tCr transgenic mice
Synthetic
FITC-labeled dextran (FITC-DX)
Additional Detail Fields 3 fields
FITC-labeled dextran (FITC-DX)
Immature mouse DC cell line SP37a3, Murine tumor cell line EG-7, 3ll-thy1.1-OVa cells
C57Bl/6 mice, Ot-II tCr transgenic mice