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Peptide record

TPDB65996

RG102 Tumor-homing Peptides standard
11 amino acids
Basic Information
3D PDB MODEL
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TPDB65996
RG102
Tumor-homing Peptides
Cancer-related peptides
TumorHoPe2.0
standard
No
A 11-aa standard natural tumor-homing peptides peptide sequence curated from TumorHoPe2.0, with an available 3D structural model.
N-terminal: 5(6)-Carboxyfluorescein (CF), Methotrexate (MTX)
Sequence
RVDPAYQVRFL
Physicochemical Analysis
C63H98N18O16
NCEGHIKMSTW
RV
1363.58
9.87
2
1
6
+1
1.22
-0.191
97.27
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
1490
109.27
2
Residue Composition
number
1
A
2
R
0
N
1
D
0
C
0
E
1
Q
0
G
0
H
0
I
1
L
0
K
0
M
1
F
1
P
0
S
0
T
0
W
1
Y
2
V
Amino Acid Distribution
A: 1 R: 2 N: 0 D: 1 C: 0 E: 0 Q: 1 G: 0 H: 0 I: 0 L: 1 K: 0 M: 0 F: 1 P: 1 S: 0 T: 0 W: 0 Y: 1 V: 2
Chemical Descriptors
11
C63H98N18O16
1363.58
9.87
+1
1.22
-0.191
RXD/QXR
5(6)-Carboxyfluorescein (CF), Methotrexate (MTX)
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Tumor cell
Homing
APN

Source & Reference

TumorHoPe2.0
TumorHoPe2
Geometry encoded functional programming of tumor homing peptides for targeted drug delivery
2021
Goyal R et al. J Control Release. 2021 May 10:333:16-27.

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
MDA-MB-231, HeLa, MCF-10A, U2-OS
Female athymic nude mice, Balb/c mice (4–5 week)
Synthetic
5(6)-Carboxyfluorescein (CF), Methotrexate (MTX)
v = D-Valine
Additional Detail Fields 3 fields
5(6)-Carboxyfluorescein (CF), Methotrexate (MTX)
MDA-MB-231, HeLa, MCF-10A, U2-OS
Female athymic nude mice, Balb/c mice (4–5 week)