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Peptide record

TPDB65988

Tumor-homing Peptides standard
8 amino acids
Basic Information
3D PDB MODEL
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TPDB65988
Tumor-homing Peptides
Cancer-related peptides
TumorHoPe2.0
standard
No
A 8-aa standard natural tumor-homing peptides peptide sequence curated from TumorHoPe2.0, with an available 3D structural model.
C-terminal: PEG28 N-terminal: PEG28
Sequence
RSDLTPLF
Physicochemical Analysis
C43H69N11O13
ANCEQGHIKMWYV
L
948.09
6.78
1
1
3
-0
0.51
-0.088
97.50
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
0
0.00
2
Residue Composition
number
0
A
1
R
0
N
1
D
0
C
0
E
0
Q
0
G
0
H
0
I
2
L
0
K
0
M
1
F
1
P
1
S
1
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 1 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 2 K: 0 M: 0 F: 1 P: 1 S: 1 T: 1 W: 0 Y: 0 V: 0
Chemical Descriptors
8
C43H69N11O13
948.09
6.78
-0
0.51
-0.088
PEG28
PEG28
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Endothelial cell, Tumor cell, Tumor vessel
Targeting
Melanoma, Pancreatic cancer
αvβ6

Source & Reference

TumorHoPe2.0
TumorHoPe2
Bi-terminal pegylated integrin-binding peptides and methods of use thereof
2022
US 11485758 B2
US 11485758 B2

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
human melanoma cell line (DX3), pancreatic cancer cell line BxPC-3
athymic nu/nu mice
Synthetic
[18F]FBA radiolabel
Additional Detail Fields 3 fields
[18F]FBA radiolabel
human melanoma cell line (DX3), pancreatic cancer cell line BxPC-3
athymic nu/nu mice