Back to search

Peptide record

TPDB65986

Tumor-homing Peptides standard
19 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB65986
Tumor-homing Peptides
Cancer-related peptides
TumorHoPe2.0
standard
No
A 19-aa standard natural tumor-homing peptides peptide sequence curated from TumorHoPe2.0, with an available 3D structural model.
Sequence
RRPYILQLYENKPRRPYIL
Physicochemical Analysis
C116H186N34O27
ADCGHMFSTWV
R
2488.96
10.68
5
1
8
+4
3.48
-1.089
102.63
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
4470
179.59
5
Residue Composition
number
0
A
4
R
1
N
0
D
0
C
1
E
1
Q
0
G
0
H
2
I
3
L
1
K
0
M
0
F
3
P
0
S
0
T
0
W
3
Y
0
V
Amino Acid Distribution
A: 0 R: 4 N: 1 D: 0 C: 0 E: 1 Q: 1 G: 0 H: 0 I: 2 L: 3 K: 1 M: 0 F: 0 P: 3 S: 0 T: 0 W: 0 Y: 3 V: 0
Chemical Descriptors
19
C116H186N34O27
2488.96
10.68
+4
3.48
-1.089
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Endothelial cell, Tumor cell, Tumor vessel
Targeting
Breast cancer, Colon cancer, Pancreatic ductal adenocarcinoma
NT

Source & Reference

TumorHoPe2.0
TumorHoPe2
Nano-enabled immunotherapy in cancer
2022
US 11433143 B2
US 11433143 B2

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
4T1 breast cancer, CT26 colon cancer, pancreatic ductal adenocarcinoma (KPC) cell
BALB/c mice
Phage display library
PEGylated cholesterol , indoximod
Additional Detail Fields 3 fields
PEGylated cholesterol , indoximod
4T1 breast cancer, CT26 colon cancer, pancreatic ductal adenocarcinoma (KPC) cell
BALB/c mice