Back to search

Peptide record

TPDB65975

RG202 Tumor-homing Peptides standard
13 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB65975
RG202
Tumor-homing Peptides
Cancer-related peptides
TumorHoPe2.0
standard
No
A 13-aa standard natural tumor-homing peptides peptide sequence curated from TumorHoPe2.0, with an available 3D structural model.
N-terminal: Methotrexate (MTX), 5(6)-carboxyfluorescein (CF)
Sequence
RPDPAYQPRFKLK
Physicochemical Analysis
C75H118N22O18
NCEGHIMSTWV
P
1615.90
10.71
4
1
4
+3
3.96
-1.654
37.69
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
1490
92.21
2
Residue Composition
number
1
A
2
R
0
N
1
D
0
C
0
E
1
Q
0
G
0
H
0
I
1
L
2
K
0
M
1
F
3
P
0
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 1 R: 2 N: 0 D: 1 C: 0 E: 0 Q: 1 G: 0 H: 0 I: 0 L: 1 K: 2 M: 0 F: 1 P: 3 S: 0 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
13
C75H118N22O18
1615.90
10.71
+3
3.96
-1.654
Methotrexate (MTX), 5(6)-carboxyfluorescein (CF)
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Homing

Source & Reference

TumorHoPe2.0
TumorHoPe2
Peptide-based delivery vectors with pre-defined geometrical locks
2020
Goyal R et al. RSC Med Chem. 2020 Aug 13 11(11):1303-1313
TEMP/ E-1/36058/2019-KOL

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
MDA-MB-231 (Human breast cancer), HeLa (cervical cancer), 2-OS (osteosarcoma), MCF-10A (mammary epithelial )
Synthetic
Methotrexate (MTX), 5(6)-carboxyfluorescein (CF)
p = D-proline
Additional Detail Fields 2 fields
Methotrexate (MTX), 5(6)-carboxyfluorescein (CF)
MDA-MB-231 (Human breast cancer), HeLa (cervical cancer), 2-OS (osteosarcoma), MCF-10A (mammary epithelial )