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Peptide record

TPDB65972

RG201 Tumor-homing Peptides standard
11 amino acids
Basic Information
3D PDB MODEL
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TPDB65972
RG201
Tumor-homing Peptides
Cancer-related peptides
TumorHoPe2.0
standard
No
A 11-aa standard natural tumor-homing peptides peptide sequence curated from TumorHoPe2.0, with an available 3D structural model.
N-terminal: Methotrexate (MTX), 5(6)-carboxyfluorescein (CF)
Sequence
RPDPAYQPRFK
Physicochemical Analysis
C63H95N19O16
NCEGHILMSTWV
P
1374.57
10.41
3
1
3
+2
3.53
-1.945
9.09
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
1490
108.40
2
Residue Composition
number
1
A
2
R
0
N
1
D
0
C
0
E
1
Q
0
G
0
H
0
I
0
L
1
K
0
M
1
F
3
P
0
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 1 R: 2 N: 0 D: 1 C: 0 E: 0 Q: 1 G: 0 H: 0 I: 0 L: 0 K: 1 M: 0 F: 1 P: 3 S: 0 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
11
C63H95N19O16
1374.57
10.41
+2
3.53
-1.945
Methotrexate (MTX), 5(6)-carboxyfluorescein (CF)
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Homing

Source & Reference

TumorHoPe2.0
TumorHoPe2
Peptide-based delivery vectors with pre-defined geometrical locks
2020
Goyal R et al. RSC Med Chem. 2020 Aug 13 11(11):1303-1313
TEMP/ E-1/36058/2019-KOL

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
MDA-MB-231 (Human breast cancer), HeLa (cervical cancer), 2-OS (osteosarcoma), MCF-10A (mammary epithelial )
Synthetic
Methotrexate (MTX), 5(6)-carboxyfluorescein (CF)
p = D-proline
Additional Detail Fields 2 fields
Methotrexate (MTX), 5(6)-carboxyfluorescein (CF)
MDA-MB-231 (Human breast cancer), HeLa (cervical cancer), 2-OS (osteosarcoma), MCF-10A (mammary epithelial )