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Peptide record

TPDB65970

uCendR Tumor-homing Peptides standard
14 amino acids
Basic Information
3D PDB MODEL
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TPDB65970
uCendR
Tumor-homing Peptides
Cancer-related peptides
TumorHoPe2.0
standard
No
A 14-aa standard natural tumor-homing peptides peptide sequence curated from TumorHoPe2.0, with an available 3D structural model.
Sequence
RPARSGRSAGGSVA
Physicochemical Analysis
C52H93N23O18
NDCEQHILKMFTWY
ARGS
1328.45
12.70
3
0
4
+3
2.86
-0.650
42.14
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
0
0.00
3
Residue Composition
number
3
A
3
R
0
N
0
D
0
C
0
E
0
Q
3
G
0
H
0
I
0
L
0
K
0
M
0
F
1
P
3
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 3 R: 3 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 3 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 1 S: 3 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
14
C52H93N23O18
1328.45
12.70
+3
2.86
-0.650
CendR
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Endothelial cell, Macrophage, Fibroblast
Targeting
NRP-1

Source & Reference

TumorHoPe2.0
TumorHoPe2
Urokinase-controlled tumor penetrating peptide
2016
Gary B Braun et al. J Control Release. 2016 Jun 28:232:188-95.

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
PPC-1, 4T1, and M21 cell line
BALB/c mice
Phage Display library
T7-phage Display
FAM-labeled
Tumor penetrating
Additional Detail Fields 4 fields
FAM-labeled
PPC-1, 4T1, and M21 cell line
BALB/c mice
T7-phage Display