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Peptide record

TPDB65969

Tumor-homing Peptides standard
18 amino acids
Basic Information
3D PDB MODEL
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TPDB65969
Tumor-homing Peptides
Cancer-related peptides
TumorHoPe2.0
standard
No
A 18-aa standard natural tumor-homing peptides peptide sequence curated from TumorHoPe2.0, with an available 3D structural model.
Sequence
RPARSGRAGGSVACRGDC
Physicochemical Analysis
C67H118N30O23S2
NEQHILKMFTWY
RG
1775.98
10.75
4
1
4
+3
4.30
-0.650
32.78
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
125
7.04
4
Residue Composition
number
3
A
4
R
0
N
1
D
2
C
0
E
0
Q
4
G
0
H
0
I
0
L
0
K
0
M
0
F
1
P
2
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 3 R: 4 N: 0 D: 1 C: 2 E: 0 Q: 0 G: 4 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 1 S: 2 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
18
C67H118N30O23S2
1775.98
10.75
+3
4.30
-0.650
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Tumor cell, Tumor vessel, Tumor stem cell, Endothelial cell, Epithelial cell, Dendritic cell
Homing

Source & Reference

TumorHoPe2.0
TumorHoPe2
Methods and compositions using peptides and proteins with C-terminal elements
2019
US 10370245 B2
US 10370245 B2

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
PPC-1, PC-3, Du-145, 4T1, MIA PaCa-2, PDAC1.3, B16F10, M21, and MDA-MB-435 cell line
BALB/c athymic nude mice
Phage Display library
T7 phage display library
nanoparticles, nanoworms, 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[maleimide(polyethylene glycol)2000 DSPE-PEG2000-maleimide]
Additional Detail Fields 4 fields
nanoparticles, nanoworms, 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[maleimide(polyethylene glycol)2000 DSPE-PEG2000-maleimide]
PPC-1, PC-3, Du-145, 4T1, MIA PaCa-2, PDAC1.3, B16F10, M21, and MDA-MB-435 cell line
BALB/c athymic nude mice
T7 phage display library