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Peptide record

TPDB65968

Tumor-homing Peptides standard
8 amino acids
Basic Information
3D PDB MODEL
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TPDB65968
Tumor-homing Peptides
Cancer-related peptides
TumorHoPe2.0
standard
No
A 8-aa standard natural tumor-homing peptides peptide sequence curated from TumorHoPe2.0, with an available 3D structural model.
Sequence
RNWELRLK
Physicochemical Analysis
C50H83N17O12
ADCQGHIMFPSTYV
RL
1114.32
11.32
3
1
3
+2
2.08
-1.650
97.50
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
5500
493.58
1
Residue Composition
number
0
A
2
R
1
N
0
D
0
C
1
E
0
Q
0
G
0
H
0
I
2
L
1
K
0
M
0
F
0
P
0
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 2 N: 1 D: 0 C: 0 E: 1 Q: 0 G: 0 H: 0 I: 0 L: 2 K: 1 M: 0 F: 0 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
8
C50H83N17O12
1114.32
11.32
+2
2.08
-1.650
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Tumor cell
Targeting
Breast cancer
Her-2

Source & Reference

TumorHoPe2.0
TumorHoPe2
A Novel Homodimer Peptide-Drug Conjugate Improves the Efficacy of HER2-Positive Breast Cancer Therapy
2023
Liu S et al. nt J Mol Sci. 2023 Feb 27 24(5):4590

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
SK-BR-3, MCF-7
Female Balb/c mice
Synthetic
Doxorubicin
Additional Detail Fields 3 fields
Doxorubicin
SK-BR-3, MCF-7
Female Balb/c mice