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Peptide record

TPDB65966

Tumor-homing Peptides standard
8 amino acids
Basic Information
3D PDB MODEL
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TPDB65966
Tumor-homing Peptides
Cancer-related peptides
TumorHoPe2.0
standard
No
A 8-aa standard natural tumor-homing peptides peptide sequence curated from TumorHoPe2.0, with an available 3D structural model.
Sequence
RNGRGPDC
Physicochemical Analysis
C32H55N15O12S1
AEQHILKMFSTWYV
RG
873.94
9.01
2
1
0
+1
3.50
-1.987
0.00
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
0
0.00
2
Residue Composition
number
0
A
2
R
1
N
1
D
1
C
0
E
0
Q
2
G
0
H
0
I
0
L
0
K
0
M
0
F
1
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 2 N: 1 D: 1 C: 1 E: 0 Q: 0 G: 2 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 1 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
8
C32H55N15O12S1
873.94
9.01
+1
3.50
-1.987
NGR
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Tumor cell
Homing
Colorectal cancer, Cervical cancer, tongue Squamous cell carcinoma

Source & Reference

TumorHoPe2.0
TumorHoPe2
Tumor pH-shiftable coating and the nucleus-directed nanoparticles facilitate the targeted chemotherapy and gene therapy against multiple cancers and use thereof
2023
US 11690803 B2
US 11690803 B2

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
HCT116 colorectal cancer cell line, HeLa cervical cancer cell line, CT26 colon carcinoma cell line, SAS tongue squamous cell carcinoma cell line
6-week old BALB/c mice, nude (nu/nu) mice
Synthetic
oxaliplatin-loaded liposomes, TAT peptide (CAYGRKKRRQRRR)
Additional Detail Fields 3 fields
oxaliplatin-loaded liposomes, TAT peptide (CAYGRKKRRQRRR)
HCT116 colorectal cancer cell line, HeLa cervical cancer cell line, CT26 colon carcinoma cell line, SAS tongue squamous cell carcinoma cell line
6-week old BALB/c mice, nude (nu/nu) mice