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Peptide record

TPDB65958

Tumor-homing Peptides standard
5 amino acids
Basic Information
3D PDB MODEL
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TPDB65958
Tumor-homing Peptides
Cancer-related peptides
TumorHoPe2.0
standard
No
A 5-aa standard natural tumor-homing peptides peptide sequence curated from TumorHoPe2.0, with an available 3D structural model.
Sequence
RGDYC
Physicochemical Analysis
C24H36N8O9S1
ANEQHILKMFPSTWV
RDCGY
612.66
6.09
1
1
1
-0
0.87
-1.440
0.00
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
1490
243.20
2
Residue Composition
number
0
A
1
R
0
N
1
D
1
C
0
E
0
Q
1
G
0
H
0
I
0
L
0
K
0
M
0
F
0
P
0
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 1 C: 1 E: 0 Q: 0 G: 1 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
5
C24H36N8O9S1
612.66
6.09
-0
0.87
-1.440
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Endothelial cell, Tumor cell, Tumor vessel
Targeting
Breast cancer, Colon cancer, Pancreatic ductal adenocarcinoma
αvβ6

Source & Reference

TumorHoPe2.0
TumorHoPe2
Nano-enabled immunotherapy in cancer
2022
US 11433143 B2
US 11433143 B2

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
4T1 breast cancer, CT26 colon cancer, pancreatic ductal adenocarcinoma (KPC) cell
BALB/c mice
Phage display library
PEGylated cholesterol , indoximod
Cyclic
Additional Detail Fields 3 fields
PEGylated cholesterol , indoximod
4T1 breast cancer, CT26 colon cancer, pancreatic ductal adenocarcinoma (KPC) cell
BALB/c mice