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Peptide record

TPDB65957

Tumor-homing Peptides standard
4 amino acids
Basic Information
3D PDB MODEL
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TPDB65957
Tumor-homing Peptides
Cancer-related peptides
TumorHoPe2.0
standard
No
A 4-aa standard natural tumor-homing peptides peptide sequence curated from TumorHoPe2.0, with an available 3D structural model.
Sequence
RGDV
Physicochemical Analysis
C17H31N7O7
ANCEQHILKMFPSTWY
RDGV
445.48
6.78
1
1
1
-0
2.12
-1.050
72.50
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
0
0.00
0
Residue Composition
number
0
A
1
R
0
N
1
D
0
C
0
E
0
Q
1
G
0
H
0
I
0
L
0
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 1 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
4
C17H31N7O7
445.48
6.78
-0
2.12
-1.050
RGD
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Tumor cell
Homing
Acute nonlymphocytic leukemia
integrin

Source & Reference

TumorHoPe2.0
TumorHoPe2
Preparation and biological evaluation of tumor-specific Ara-C liposomal preparations containing RGDV motif
2012
Fei Wang et al. J Pharm Sci. 2012 Dec 101(12):4559-68.

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
male Kunming mice (18–22 g)
Synthetic
Cytarabine (1-$-D-Arabinofuranosylcytosine, Ara C,
Additional Detail Fields 2 fields
Cytarabine (1-$-D-Arabinofuranosylcytosine, Ara C,
male Kunming mice (18–22 g)