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Peptide record

TPDB65955

ST1-59 Tumor-homing Peptides standard
9 amino acids
Basic Information
3D PDB MODEL
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TPDB65955
ST1-59
Tumor-homing Peptides
Cancer-related peptides
TumorHoPe2.0
standard
No
A 9-aa standard natural tumor-homing peptides peptide sequence curated from TumorHoPe2.0, with an available 3D structural model.
C-terminal: amides N-terminal: tert-butyloxycarbonyl (Boc)
Sequence
RGDLMKLAK
Physicochemical Analysis
C44H82N14O12S1
NCEQHIFPSTWYV
LK
1031.28
10.59
3
1
4
+2
2.51
-0.544
97.78
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
0
0.00
0
Residue Composition
number
1
A
1
R
0
N
1
D
0
C
0
E
0
Q
1
G
0
H
0
I
2
L
2
K
1
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 1 N: 0 D: 1 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 0 L: 2 K: 2 M: 1 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
9
C44H82N14O12S1
1031.28
10.59
+2
2.51
-0.544
amides
tert-butyloxycarbonyl (Boc)
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Tumor cell, Endothelial cell
Targeting
Pancreatic cancer, Breast cancer, Colorectal cancer, Prostate cancer, Oral Squamous cell carcinoma
αvβ6

Source & Reference

TumorHoPe2.0
TumorHoPe2
Alpha(v)beta(6) integrin-binding peptides and methods of use thereof
2021
US 11185601 B2
US 11185601 B2

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
DX3Puro, DX3Puroβ6, DX3/EmGFP, DX3/ITG β6 mCherry
Synthetic
PEG12 (PEG 800), PEG28 (PEG 1,500)
Additional Detail Fields 2 fields
PEG12 (PEG 800), PEG28 (PEG 1,500)
DX3Puro, DX3Puroβ6, DX3/EmGFP, DX3/ITG β6 mCherry