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Peptide record

TPDB65941

RG301 Tumor-homing Peptides standard
19 amino acids
Basic Information
3D PDB MODEL
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TPDB65941
RG301
Tumor-homing Peptides
Cancer-related peptides
TumorHoPe2.0
standard
No
A 19-aa standard natural tumor-homing peptides peptide sequence curated from TumorHoPe2.0, with an available 3D structural model.
N-terminal: 5(6)-Carboxyfluorescein (CF), Methotrexate (MTX)
Sequence
RADPAYQARFLGKRKFLCL
Physicochemical Analysis
C103H165N31O24S1
NEHIMSTWV
ARL
2253.70
10.70
5
1
9
+4
1.05
-0.353
77.37
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
1490
66.11
3
Residue Composition
number
3
A
3
R
0
N
1
D
1
C
0
E
1
Q
1
G
0
H
0
I
3
L
2
K
0
M
2
F
1
P
0
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 3 R: 3 N: 0 D: 1 C: 1 E: 0 Q: 1 G: 1 H: 0 I: 0 L: 3 K: 2 M: 0 F: 2 P: 1 S: 0 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
19
C103H165N31O24S1
2253.70
10.70
+4
1.05
-0.353
5(6)-Carboxyfluorescein (CF), Methotrexate (MTX)
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Homing

Source & Reference

TumorHoPe2.0
TumorHoPe2
Molecular hybridization combining tumor homing and penetrating peptide domains for cellular targeting
2022
Goyal R et al. Drug Deliv Transl Res. 2022 Jun 12(6)

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
HEK-293, MDA-MB-231, HeLa
Synthetic
5(6)-carboxyfluorescein (CF), methotrexate (MTX)
Additional Detail Fields 2 fields
5(6)-carboxyfluorescein (CF), methotrexate (MTX)
HEK-293, MDA-MB-231, HeLa