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Peptide record

TPDB65939

Peptide 1 Tumor-homing Peptides standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB65939
Peptide 1
Tumor-homing Peptides
Cancer-related peptides
TumorHoPe2.0
standard
No
A 12-aa standard natural tumor-homing peptides peptide sequence curated from TumorHoPe2.0, with an available 3D structural model.
C-terminal: (KKKK) as a linker
Sequence
QYWNIQNGPYGG
Physicochemical Analysis
C64H85N17O19
ARDCEHLKMFSTV
G
1396.48
5.88
0
0
4
-0
-1.56
-1.317
32.50
Mammalian: 0.8 hour Yeast: 10 min E.coli: >10 hour
8480
607.24
6
Residue Composition
number
0
A
0
R
2
N
0
D
0
C
0
E
2
Q
3
G
0
H
1
I
0
L
0
K
0
M
0
F
1
P
0
S
0
T
1
W
2
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 2 D: 0 C: 0 E: 0 Q: 2 G: 3 H: 0 I: 1 L: 0 K: 0 M: 0 F: 0 P: 1 S: 0 T: 0 W: 1 Y: 2 V: 0
Chemical Descriptors
12
C64H85N17O19
1396.48
5.88
-0
-1.56
-1.317
(KKKK) as a linker
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Tumor cell
Targeting
osteosarcoma

Source & Reference

TumorHoPe2.0
TumorHoPe2
Enhancement of T cell infiltration via tumor-targeted Th9 cell delivery improves the efficacy of antitumor immunotherapy of solid tumors
2022
Tao Chen et al. Bioact Mater. 2022 Dec 5:23:508-523.

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
K7M2, HOS, 3T3, LLC, K7M2-Luci-OVA, K7M2- mCherry, HOS-Luci cell line
Female Balb/c (5-to-8 week-old) mice, Immune compromised Nod/SCID mice (5- to-8 week-old), DO11.10 mice, B6-G/R mice
Phage display library
Ph.D.-12 phage display peptide library
Cy5.5
Additional Detail Fields 4 fields
Cy5.5
K7M2, HOS, 3T3, LLC, K7M2-Luci-OVA, K7M2- mCherry, HOS-Luci cell line
Female Balb/c (5-to-8 week-old) mice, Immune compromised Nod/SCID mice (5- to-8 week-old), DO11.10 mice, B6-G/R mice
Ph.D.-12 phage display peptide library