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Peptide record

TPDB65935

Peptide 2 Tumor-homing Peptides standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB65935
Peptide 2
Tumor-homing Peptides
Cancer-related peptides
TumorHoPe2.0
standard
No
A 12-aa standard natural tumor-homing peptides peptide sequence curated from TumorHoPe2.0, with an available 3D structural model.
C-terminal: (KKKK) as a linker
Sequence
QMGFMTSPLHSV
Physicochemical Analysis
C58H91N15O17S2
ARNDCEIKWY
MS
1334.57
7.85
1
0
5
+0
0.32
0.300
56.67
Mammalian: 0.8 hour Yeast: 10 min E.coli: >10 hour
0
0.00
4
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
1
Q
1
G
1
H
0
I
1
L
0
K
2
M
1
F
1
P
2
S
1
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 1 H: 1 I: 0 L: 1 K: 0 M: 2 F: 1 P: 1 S: 2 T: 1 W: 0 Y: 0 V: 1
Chemical Descriptors
12
C58H91N15O17S2
1334.57
7.85
+0
0.32
0.300
(KKKK) as a linker
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Tumor cell
Targeting
osteosarcoma

Source & Reference

TumorHoPe2.0
TumorHoPe2
Enhancement of T cell infiltration via tumor-targeted Th9 cell delivery improves the efficacy of antitumor immunotherapy of solid tumors
2022
Tao Chen et al. Bioact Mater. 2022 Dec 5:23:508-523.

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
K7M2, HOS, 3T3, LLC, K7M2-Luci-OVA, K7M2- mCherry, HOS-Luci cell line
Female Balb/c (5-to-8 week-old) mice, Immune compromised Nod/SCID mice (5- to-8 week-old), DO11.10 mice, B6-G/R mice
Phage display library
Ph.D.-12 phage display peptide library
Cy5.5
Additional Detail Fields 4 fields
Cy5.5
K7M2, HOS, 3T3, LLC, K7M2-Luci-OVA, K7M2- mCherry, HOS-Luci cell line
Female Balb/c (5-to-8 week-old) mice, Immune compromised Nod/SCID mice (5- to-8 week-old), DO11.10 mice, B6-G/R mice
Ph.D.-12 phage display peptide library