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Peptide record

TPDB65934

Fl-NrTP1 Tumor-homing Peptides standard
14 amino acids
Basic Information
3D PDB MODEL
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TPDB65934
Fl-NrTP1
Tumor-homing Peptides
Cancer-related peptides
TumorHoPe2.0
standard
No
A 14-aa standard natural tumor-homing peptides peptide sequence curated from TumorHoPe2.0, with an available 3D structural model.
Sequence
QKYKSHGKGKSKGG
Physicochemical Analysis
C64H108N22O19
ARNDCEILMFPTWV
K
1489.70
10.77
6
0
1
+5
5.85
-2.193
0.00
Mammalian: 0.8 hour Yeast: 10 min E.coli: >10 hour
1490
100.02
4
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
1
Q
4
G
1
H
0
I
0
L
5
K
0
M
0
F
0
P
2
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 4 H: 1 I: 0 L: 0 K: 5 M: 0 F: 0 P: 0 S: 2 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
14
C64H108N22O19
1489.70
10.77
+5
5.85
-2.193
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Tumor cell
Targeting

Source & Reference

TumorHoPe2.0
TumorHoPe2
Insights into the uptake mechanism of NrTP, a cell-penetrating peptide preferentially targeting the nucleolus of tumour cells
2012
Gandhi Rádis-Baptista et al. Chem Biol Drug Des. 2012 Jun 79(6):907-15.

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
Human cervix epithelial carcinoma (HeLa), pancreatic adenocarcinoma (BxPC-3), ductal mammary gland carcinoma (BT-474) and murine neu roblastome (N2A)
Synthetic
Additional Detail Fields 1 fields
Human cervix epithelial carcinoma (HeLa), pancreatic adenocarcinoma (BxPC-3), ductal mammary gland carcinoma (BT-474) and murine neu roblastome (N2A)