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Peptide record

TPDB65926

Tumor-homing Peptides standard
7 amino acids
Basic Information
3D PDB MODEL
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TPDB65926
Tumor-homing Peptides
Cancer-related peptides
TumorHoPe2.0
standard
No
A 7-aa standard natural tumor-homing peptides peptide sequence curated from TumorHoPe2.0, with an available 3D structural model.
C-terminal: D-cysteine N-terminal: D-cysteine
Sequence
QDGRRGF
Physicochemical Analysis
C34H54N14O11
ANCEHILKMPSTWYV
RG
834.89
10.89
2
1
1
+1
2.32
-2.000
0.00
Mammalian: 0.8 hour Yeast: 10 min E.coli: >10 hour
0
0.00
1
Residue Composition
number
0
A
2
R
0
N
1
D
0
C
0
E
1
Q
2
G
0
H
0
I
0
L
0
K
0
M
1
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 2 N: 0 D: 1 C: 0 E: 0 Q: 1 G: 2 H: 0 I: 0 L: 0 K: 0 M: 0 F: 1 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
7
C34H54N14O11
834.89
10.89
+1
2.32
-2.000
D-cysteine
D-cysteine
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Tumor cell
Targeting
Bladder cancer
ανβ3 integrin

Source & Reference

TumorHoPe2.0
TumorHoPe2
Bladder cancer specific ligand peptides
2015
US 8946379 B2
US 8946379 B2

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
Human bladder cancer cell line 5637
Athymic nude mice
Synthetic/ Recombinant
Cy5.5
At 5th position, D-amino acids
Additional Detail Fields 3 fields
Cy5.5
Human bladder cancer cell line 5637
Athymic nude mice