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Peptide record

TPDB65909

Tumor-homing Peptides standard
6 amino acids
Basic Information
3D PDB MODEL
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TPDB65909
Tumor-homing Peptides
Cancer-related peptides
TumorHoPe2.0
standard
No
A 6-aa standard natural tumor-homing peptides peptide sequence curated from TumorHoPe2.0, with an available 3D structural model.
N-terminal: Fmoc protection during synthesis, removed later
Sequence
PVGLIG
Physicochemical Analysis
C26H46N6O7
ARNDCEQHKMFSTWY
G
554.69
6.02
0
0
3
-0
-0.33
1.683
178.33
Mammalian: >20 hour Yeast: >20 hour E.coli: ?
0
0.00
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
2
G
0
H
1
I
1
L
0
K
0
M
0
F
1
P
0
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 0 I: 1 L: 1 K: 0 M: 0 F: 0 P: 1 S: 0 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
6
C26H46N6O7
554.69
6.02
-0
-0.33
1.683
Fmoc protection during synthesis, removed later
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Tumor cell
Targeting
fibrosarcoma, Glioblastoma
MMP2 protein

Source & Reference

TumorHoPe2.0
TumorHoPe2
Controlled release strategy of paclitaxel by conjugating to matrix metalloproteinases-2 sensitive peptide
2016
Changjiang Huang et al. Oncotarget. 2016 Aug 9 7(32):52230-52238.

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
HT-1080 human fibrosarcoma cells, U87-MG human glioblastoma cells
Six-week-old male BALB/c nude mice
Phage display library
Paclitaxel (PTX)
Additional Detail Fields 3 fields
Paclitaxel (PTX)
HT-1080 human fibrosarcoma cells, U87-MG human glioblastoma cells
Six-week-old male BALB/c nude mice