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Peptide record

TPDB65904

Tumor-homing Peptides standard
26 amino acids
Basic Information
3D PDB MODEL
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TPDB65904
Tumor-homing Peptides
Cancer-related peptides
TumorHoPe2.0
standard
No
A 26-aa standard natural tumor-homing peptides peptide sequence curated from TumorHoPe2.0, with an available 3D structural model.
Sequence
PLFAERLKLAKLAKKLAKLAKCGKRK
Physicochemical Analysis
C135H244N40O29S1
NDQHIMSTWYV
K
2923.73
11.29
10
1
12
+9
6.44
-0.331
109.23
Mammalian: >20 hour Yeast: >20 hour E.coli: ?
0
0.00
1
Residue Composition
number
5
A
2
R
0
N
0
D
1
C
1
E
0
Q
1
G
0
H
0
I
6
L
8
K
0
M
1
F
1
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 5 R: 2 N: 0 D: 0 C: 1 E: 1 Q: 0 G: 1 H: 0 I: 0 L: 6 K: 8 M: 0 F: 1 P: 1 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
26
C135H244N40O29S1
2923.73
11.29
+9
6.44
-0.331
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Tumor cell, Tumor vessel
Targeting
Breast cancer
Calpain

Source & Reference

TumorHoPe2.0
TumorHoPe2
Synergy of Iron Chelators and Therapeutic Peptide Sequences Delivered via a Magnetic Nanocarrier
2017
Gayani S Abayaweera et al. J Funct Biomater. 2017 Jun 26 8(3):23.

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
4T1 murine breast cancer cells
BALB/c mice
Synthetic
Dp44mT (iron chelator), Fe/Fe3O4 nanoparticles, dopamine anchors
Additional Detail Fields 3 fields
Dp44mT (iron chelator), Fe/Fe3O4 nanoparticles, dopamine anchors
4T1 murine breast cancer cells
BALB/c mice