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Peptide record

TPDB65899

IVO-5 Tumor-homing Peptides standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB65899
IVO-5
Tumor-homing Peptides
Cancer-related peptides
TumorHoPe2.0
standard
No
A 12-aa standard natural tumor-homing peptides peptide sequence curated from TumorHoPe2.0, with an available 3D structural model.
Sequence
NYLHNHPYGTVG
Physicochemical Analysis
C62H86N18O18
ARDCEQIKMFSW
NGHY
1371.47
7.86
2
0
4
+0
1.00
-0.925
56.67
Mammalian: 1.4 hour Yeast: 3 min E.coli: >10 hour
2980
217.28
5
Residue Composition
number
0
A
0
R
2
N
0
D
0
C
0
E
0
Q
2
G
2
H
0
I
1
L
0
K
0
M
0
F
1
P
0
S
1
T
0
W
2
Y
1
V
Amino Acid Distribution
A: 0 R: 0 N: 2 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 2 I: 0 L: 1 K: 0 M: 0 F: 0 P: 1 S: 0 T: 1 W: 0 Y: 2 V: 1
Chemical Descriptors
12
C62H86N18O18
1371.47
7.86
+0
1.00
-0.925
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Tumor vessel
Targeting
Oral cancer

Source & Reference

TumorHoPe2.0
TumorHoPe2
Tumor-targeting peptides and uses thereof
2013
US 8394758 B2
US 8394758 B2

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
SAS cells (an oral cancer cell line)
SCID mice (4-6 weeks of age
Phage display library
M13
doxorubicin
Additional Detail Fields 4 fields
doxorubicin
SAS cells (an oral cancer cell line)
SCID mice (4-6 weeks of age
M13