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Peptide record

TPDB65894

Tumor-homing Peptides standard
6 amino acids
Basic Information
3D PDB MODEL
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TPDB65894
Tumor-homing Peptides
Cancer-related peptides
TumorHoPe2.0
standard
No
A 6-aa standard natural tumor-homing peptides peptide sequence curated from TumorHoPe2.0, with an available 3D structural model.
Sequence
NGQGEQ
Physicochemical Analysis
C23H37N9O12
ARDCHILKMFPSTWYV
QG
631.60
3.29
0
1
0
-1
3.62
-2.467
0.00
Mammalian: 1.4 hour Yeast: 3 min E.coli: >10 hour
0
0.00
3
Residue Composition
number
0
A
0
R
1
N
0
D
0
C
1
E
2
Q
2
G
0
H
0
I
0
L
0
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 1 D: 0 C: 0 E: 1 Q: 2 G: 2 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
6
C23H37N9O12
631.60
3.29
-1
3.62
-2.467
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Tumor cell
Homing
α3β1 integrin

Source & Reference

TumorHoPe2.0
TumorHoPe2
Robust, tumor-homing and redox-sensitive polymersomal doxorubicin: A superior alternative to Doxil and Caelyx?
2016
Yan Zou et al. J Control Release. 2016 Oct 10:239:149-58.

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
A549 lung cancer cells
Synthetic
doxorubicin
Cyclic
Additional Detail Fields 2 fields
doxorubicin
A549 lung cancer cells