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Peptide record

TPDB65887

C7 Tumor-homing Peptides standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB65887
C7
Tumor-homing Peptides
Cancer-related peptides
TumorHoPe2.0
standard
No
A 12-aa standard natural tumor-homing peptides peptide sequence curated from TumorHoPe2.0, with an available 3D structural model.
C-terminal: Amidated
Sequence
MHTAPGTGTALS
Physicochemical Analysis
C47H78N14O17S1
RNDCEQIKFWYV
T
1143.28
7.85
1
0
4
+0
0.85
0.067
49.17
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
4
Residue Composition
number
2
A
0
R
0
N
0
D
0
C
0
E
0
Q
2
G
1
H
0
I
1
L
0
K
1
M
0
F
1
P
1
S
3
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 2 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 1 I: 0 L: 1 K: 0 M: 1 F: 0 P: 1 S: 1 T: 3 W: 0 Y: 0 V: 0
Chemical Descriptors
12
C47H78N14O17S1
1143.28
7.85
+0
0.85
0.067
Amidated
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Tumor cell
Homing
folate receptor alpha (FRα)

Source & Reference

TumorHoPe2.0
TumorHoPe2
Utilizing glutathione-triggered nanoparticles to enhance chemotherapy of lung cancer by reprograming the tumor microenvironment
2018
Tao Cui et al. Int J Pharm. 2018 Dec 1 552(1-2):16-26

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
J774A.1 cells and A549 cells
male balb/c nude mice (20 ± 2 g),
Synthetic
Additional Detail Fields 2 fields
J774A.1 cells and A549 cells
male balb/c nude mice (20 ± 2 g),