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Peptide record

TPDB65881

tfRFP Tumor-homing Peptides standard
14 amino acids
Basic Information
3D PDB MODEL
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TPDB65881
tfRFP
Tumor-homing Peptides
Cancer-related peptides
TumorHoPe2.0
standard
No
A 14-aa standard natural tumor-homing peptides peptide sequence curated from TumorHoPe2.0, with an available 3D structural model.
Sequence
LTVSPWYLTVSPWY
Physicochemical Analysis
C86H118N16O21
ARNDCEQGHIKMF
LPSTWYV
1711.98
5.88
0
0
8
-0
-5.12
0.386
97.14
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
13980
816.60
6
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
2
L
0
K
0
M
0
F
2
P
2
S
2
T
2
W
2
Y
2
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 2 K: 0 M: 0 F: 0 P: 2 S: 2 T: 2 W: 2 Y: 2 V: 2
Chemical Descriptors
14
C86H118N16O21
1711.98
5.88
-0
-5.12
0.386
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Tumor cell (5-8F cell)
Targeting
nasopharyngeal cancer

Source & Reference

TumorHoPe2.0
TumorHoPe2
An (125)I-labeled octavalent peptide fluorescent nanoprobe for tumor-homing imaging in vivo
2012
Haiming Luo et al. Chem Biol Drug Des. 2023 Dec 102(6):1421-1434.

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
Human nasopharyngeal cancer 5e8F cells
Five-week-old female BLAB/c nu/nu mice
Natural
125I-Octa-FNP, 125I-tfRFP, 125I-peptide
Additional Detail Fields 3 fields
125I-Octa-FNP, 125I-tfRFP, 125I-peptide
Human nasopharyngeal cancer 5e8F cells
Five-week-old female BLAB/c nu/nu mice