Back to search

Peptide record

TPDB65874

Tumor-homing Peptides standard
20 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB65874
Tumor-homing Peptides
Cancer-related peptides
TumorHoPe2.0
standard
No
A 20-aa standard natural tumor-homing peptides peptide sequence curated from TumorHoPe2.0, with an available 3D structural model.
Sequence
LNCDYQGTNPATSVSVPCTV
Physicochemical Analysis
C86H137N23O32S2
REHIKMFW
TV
2069.29
3.10
0
1
6
-1
2.30
0.030
68.00
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
1615
78.05
11
Residue Composition
number
1
A
0
R
2
N
1
D
2
C
0
E
1
Q
1
G
0
H
0
I
1
L
0
K
0
M
0
F
2
P
2
S
3
T
0
W
1
Y
3
V
Amino Acid Distribution
A: 1 R: 0 N: 2 D: 1 C: 2 E: 0 Q: 1 G: 1 H: 0 I: 0 L: 1 K: 0 M: 0 F: 0 P: 2 S: 2 T: 3 W: 0 Y: 1 V: 3
Chemical Descriptors
20
C86H137N23O32S2
2069.29
3.10
-1
2.30
0.030
Evidence Records 2 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Tumor cell, Tumor vessel, Tumor stem cell, Endothelial cell,
Homing
Brain cancer
gC1q/p32 receptor

Source & Reference

TumorHoPe2.0
TumorHoPe2
Targeted delivery system and methods of use therefor
2022
US 11512110 B2
US 11512110 B2

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
Athymic nude mice, ApoE null mice
Phage display library
T7 phage / cyclic Cx7C and linear X7 peptide library
Nanoworms(NWs), polyethylene glycol
Evidence 2 Activity

Activity

Tumor-homing Peptides

Target

Tumor cell, Tumor vessel, Tumor stem cell, Endothelial cell, Epithelial cell, Dendritic cell
Homing
Brain cancer

Source & Reference

TumorHoPe2.0
TumorHoPe2
Methods and compositions using peptides and proteins with C-terminal elements
2019
US 10370245 B2
US 10370245 B2

Other

PPC-1, PC-3, Du-145, 4T1, MIA PaCa-2, PDAC1.3, B16F10, M21, and MDA-MB-435 cell line
BALB/c athymic nude mice
Phage Display library
T7 phage display library
nanoparticles, nanoworms, 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[maleimide(polyethylene glycol)2000 DSPE-PEG2000-maleimide]
Additional Detail Fields 4 fields
Nanoworms(NWs), polyethylene glycol nanoparticles, nanoworms, 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[maleimide(polyethylene glycol)2000 DSPE-PEG2000-maleimide]
PPC-1, PC-3, Du-145, 4T1, MIA PaCa-2, PDAC1.3, B16F10, M21, and MDA-MB-435 cell line
Athymic nude mice, ApoE null mice BALB/c athymic nude mice
T7 phage / cyclic Cx7C and linear X7 peptide library T7 phage display library