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Peptide record

TPDB65865

TU17 Tumor-homing Peptides standard
19 amino acids
Basic Information
3D PDB MODEL
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TPDB65865
TU17
Tumor-homing Peptides
Cancer-related peptides
TumorHoPe2.0
standard
No
A 19-aa standard natural tumor-homing peptides peptide sequence curated from TumorHoPe2.0, with an available 3D structural model.
Sequence
KLLNLISKLFGGRPARPAR
Physicochemical Analysis
C96H167N31O22
DCEQHMTWYV
L
2107.58
12.71
5
0
8
+5
1.86
-0.184
113.16
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
0
0.00
2
Residue Composition
number
2
A
3
R
1
N
0
D
0
C
0
E
0
Q
2
G
0
H
1
I
4
L
2
K
0
M
1
F
2
P
1
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 2 R: 3 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 0 I: 1 L: 4 K: 2 M: 0 F: 1 P: 2 S: 1 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
19
C96H167N31O22
2107.58
12.71
+5
1.86
-0.184
CendR
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Tumor cell
Homing
Colon carcinoma
Neuropilin-1 (NRP-1)

Source & Reference

TumorHoPe2.0
TumorHoPe2
Necrosis-inducing peptide has the beneficial effect on killing tumor cells through neuropilin (NRP-1) targeting
2016
Ji-Young Kim et al. Oncotarget. 2016 May 31 7(22):32449-61.

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
CT26 colon carcinoma cell line
BALB/c mice (males, 6 weeks-old)
Synthetic
MTD
Additional Detail Fields 3 fields
MTD
CT26 colon carcinoma cell line
BALB/c mice (males, 6 weeks-old)