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Peptide record

TPDB65863

Tumor-homing Peptides standard
17 amino acids
Basic Information
3D PDB MODEL
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TPDB65863
Tumor-homing Peptides
Cancer-related peptides
TumorHoPe2.0
standard
No
A 17-aa standard natural tumor-homing peptides peptide sequence curated from TumorHoPe2.0, with an available 3D structural model.
Sequence
KKKGGYHWYGYTPQNVI
Physicochemical Analysis
C97H139N25O24
ARDCELMFS
GKY
2039.32
10.06
4
0
6
+3
0.64
-1.265
40.00
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
9970
488.89
6
Residue Composition
number
0
A
0
R
1
N
0
D
0
C
0
E
1
Q
3
G
1
H
1
I
0
L
3
K
0
M
0
F
1
P
0
S
1
T
1
W
3
Y
1
V
Amino Acid Distribution
A: 0 R: 0 N: 1 D: 0 C: 0 E: 0 Q: 1 G: 3 H: 1 I: 1 L: 0 K: 3 M: 0 F: 0 P: 1 S: 0 T: 1 W: 1 Y: 3 V: 1
Chemical Descriptors
17
C97H139N25O24
2039.32
10.06
+3
0.64
-1.265
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Tumor cell
Homing
Breast cancer
EGFR

Source & Reference

TumorHoPe2.0
TumorHoPe2
A Dual-Reporter Platform for Screening Tumor-Targeted Extracellular Vesicles
2022
Kanada M et al. Pharmaceutics. 2022 Feb 22 14(3):475.

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
MDA-MB-231, HEK293FT
Synthetic
Dioleoylphosphoethanolamine N-hydroxysuccinimide (DOPE-NHS ), Palmitoylation sequence (MLCCMRRTKQ) fused Red enhanced Nano-lantern (ReNL)
Additional Detail Fields 2 fields
Dioleoylphosphoethanolamine N-hydroxysuccinimide (DOPE-NHS ), Palmitoylation sequence (MLCCMRRTKQ) fused Red enhanced Nano-lantern (ReNL)
MDA-MB-231, HEK293FT