Peptide record

TPDB65851

Tumor-homing Peptides modified_plain modified
10 amino acids
Basic Information
3D PDB MODEL
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TPDB65851
Tumor-homing Peptides
Cancer-related peptides
TumorHoPe2.0
modified_plain
Yes
A 10-aa modified tumor-homing peptides peptide sequence curated from TumorHoPe2.0, with an available 3D structural model.
Modified, details unspecified
Sequence
IFLLWQRXXX
Physicochemical Analysis
C49H74N12O9
ANDCEGHKMPSTYV
L
975.20
11.05
1
0
5
+1
-3.02
0.600
117.00
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
5500
563.99
1
Residue Composition
number
0
A
1
R
0
N
0
D
0
C
0
E
1
Q
0
G
0
H
1
I
2
L
0
K
0
M
1
F
0
P
0
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 0 H: 0 I: 1 L: 2 K: 0 M: 0 F: 1 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
10
C49H74N12O9
975.20
11.05
+1
-3.02
0.600
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Tumor vessel, Tumor cell, Endothelial cell
Homing
Lung cancer
annexin 1

Source & Reference

TumorHoPe2.0
TumorHoPe2
Methods and compositions related to annexin 1-binding compounds
2017
US 9610359 B2
US 9610359 B2

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
Mouse melanoma B16F1 cells
C57BL/6 female mice (8-10 weeks old)
Phage Display library
IF7 phage
FITC
X is independently a polar or charged amino acid
Additional Detail Fields 4 fields
FITC
Mouse melanoma B16F1 cells
C57BL/6 female mice (8-10 weeks old)
IF7 phage