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Peptide record

TPDB65833

D[CDX] Tumor-homing Peptides standard
16 amino acids
Basic Information
3D PDB MODEL
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TPDB65833
D[CDX]
Tumor-homing Peptides
Cancer-related peptides
TumorHoPe2.0
standard
No
A 16-aa standard natural tumor-homing peptides peptide sequence curated from TumorHoPe2.0, with an available 3D structural model.
Sequence
GREIRTGRAERWSEKF
Physicochemical Analysis
C85H136N30O25
NDCQHLMPYV
R
1978.20
11.15
5
3
4
+2
7.12
-1.656
30.63
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
5500
278.03
2
Residue Composition
number
1
A
4
R
0
N
0
D
0
C
3
E
0
Q
2
G
0
H
1
I
0
L
1
K
0
M
1
F
0
P
1
S
1
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 4 N: 0 D: 0 C: 0 E: 3 Q: 0 G: 2 H: 0 I: 1 L: 0 K: 1 M: 0 F: 1 P: 0 S: 1 T: 1 W: 1 Y: 0 V: 0
Chemical Descriptors
16
C85H136N30O25
1978.20
11.15
+2
7.12
-1.656
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

brain blood vessel
Homing
Glioma
nicotine acetylcholine receptors (nAChRs)

Source & Reference

TumorHoPe2.0
TumorHoPe2
Non-immunogenic, low-toxicity and effective glioma targeting MTI-31 liposomes
2019
Xiaoyi Wang et al. J Control Release. 2019 Dec 28:316:381-392.

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
U87 glioblastoma cell line
Male BALB/c nude mice, ICR mice of 4~6 weeks
Synthetic
MTI-31, Polyethylene glycol (PEG), DSPE (distearoylphosphatidylethanolamine)
Additional Detail Fields 3 fields
MTI-31, Polyethylene glycol (PEG), DSPE (distearoylphosphatidylethanolamine)
U87 glioblastoma cell line
Male BALB/c nude mice, ICR mice of 4~6 weeks