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Peptide record

TPDB65830

A15 Tumor-homing Peptides modified_plain modified
15 amino acids
Basic Information
3D PDB MODEL
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TPDB65830
A15
Tumor-homing Peptides
Cancer-related peptides
TumorHoPe2.0
modified_plain
Yes
A 15-aa modified tumor-homing peptides peptide sequence curated from TumorHoPe2.0, with an available 3D structural model.
Modified, details unspecified
Sequence
GNQEQVSPLTLLKXC
Physicochemical Analysis
C65H112N18O22S1
ARDHIMFWY
L
1529.77
6.28
1
1
4
-0
3.47
-0.220
97.33
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
6
Residue Composition
number
0
A
0
R
1
N
0
D
1
C
1
E
2
Q
1
G
0
H
0
I
3
L
1
K
0
M
0
F
1
P
1
S
1
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 0 N: 1 D: 0 C: 1 E: 1 Q: 2 G: 1 H: 0 I: 0 L: 3 K: 1 M: 0 F: 0 P: 1 S: 1 T: 1 W: 0 Y: 0 V: 1
Chemical Descriptors
15
C65H112N18O22S1
1529.77
6.28
-0
3.47
-0.220
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Vascular endothelial cell
Targeting
Blood clot

Source & Reference

TumorHoPe2.0
TumorHoPe2
Self-Amplifying Nanotherapeutic Drugs Homing to Tumors in a Manner of Chain Reaction
2021
Wang Y et al. Adv Mater.2021 Feb 33(7):e2002094.

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
C26 tumor-bearing BALB/c mice.
Synthetic
Poly(L-glutamic acid)-graft-maleimide poly(ethylene glycol)/combretastatin A4 conjugate (PLG-CA4)
Additional Detail Fields 2 fields
Poly(L-glutamic acid)-graft-maleimide poly(ethylene glycol)/combretastatin A4 conjugate (PLG-CA4)
C26 tumor-bearing BALB/c mice.