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Peptide record

TPDB65829

LyP-1 Tumor-homing Peptides standard
7 amino acids
Basic Information
3D PDB MODEL
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TPDB65829
LyP-1
Tumor-homing Peptides
Cancer-related peptides
TumorHoPe2.0
standard
No
A 7-aa standard natural tumor-homing peptides peptide sequence curated from TumorHoPe2.0, with an available 3D structural model.
N-terminal: 5-FAM (5-Carboxyfluorescein)
Sequence
GNKRTRG
Physicochemical Analysis
C30H57N15O10
ADCEQHILMFPSWYV
RG
787.88
12.41
3
0
0
+3
3.19
-2.557
0.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
2
Residue Composition
number
0
A
2
R
1
N
0
D
0
C
0
E
0
Q
2
G
0
H
0
I
0
L
1
K
0
M
0
F
0
P
0
S
1
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 2 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 0 I: 0 L: 0 K: 1 M: 0 F: 0 P: 0 S: 0 T: 1 W: 0 Y: 0 V: 0
Chemical Descriptors
7
C30H57N15O10
787.88
12.41
+3
3.19
-2.557
5-FAM (5-Carboxyfluorescein)
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Tumor cell
Homing
Breast cancer
p32

Source & Reference

TumorHoPe2.0
TumorHoPe2
A novel small molecule inhibitor of p32 mitochondrial protein overexpressed in glioma
2017
Yenugonda V et al. J Transl Med. 2017 Oct 18 15(1):210

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
SF188, U373, UW426, GBM8 stem cell line
Synthetic
5-FAM (5-Carboxyfluorescein) at N-terminus
Additional Detail Fields 2 fields
5-FAM (5-Carboxyfluorescein) at N-terminus
SF188, U373, UW426, GBM8 stem cell line