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Peptide record

TPDB65788

Tumor-homing Peptides standard
5 amino acids
Basic Information
3D PDB MODEL
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TPDB65788
Tumor-homing Peptides
Cancer-related peptides
TumorHoPe2.0
standard
No
A 5-aa standard natural tumor-homing peptides peptide sequence curated from TumorHoPe2.0, with an available 3D structural model.
C-terminal: NHS (0.008 m) and EDAC (0.006 m) were added to activate the free carboxyl groups of serine.
Sequence
GCGNS
Physicochemical Analysis
C14H24N6O8S1
ARDEQHILKMFPTWYV
G
436.44
5.33
0
0
0
-0
0.33
-0.520
0.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
3
Residue Composition
number
0
A
0
R
1
N
0
D
1
C
0
E
0
Q
2
G
0
H
0
I
0
L
0
K
0
M
0
F
0
P
1
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 1 D: 0 C: 1 E: 0 Q: 0 G: 2 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 0 S: 1 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
5
C14H24N6O8S1
436.44
5.33
-0
0.33
-0.520
NHS (0.008 m) and EDAC (0.006 m) were added to activate the free carboxyl groups of serine.
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Tumor cell
Targeting
Breast cancer

Source & Reference

TumorHoPe2.0
TumorHoPe2
Self-Assembled Peptide-Based Biocomposites for Near-Infrared Light Triggered Drug Release to Tumor Cells
2020
Daso RE et al. Biotechnol J. 2020 Dec 15(12):e2000128

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
MCF-7 cell line
Synthetic
Fmoc-Leu- Ser-GCGNS (FLS)
Additional Detail Fields 2 fields
Fmoc-Leu- Ser-GCGNS (FLS)
MCF-7 cell line