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Peptide record

TPDB65786

CRGDC peptide Tumor-homing Peptides standard
10 amino acids
Basic Information
3D PDB MODEL
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TPDB65786
CRGDC peptide
Tumor-homing Peptides
Cancer-related peptides
TumorHoPe2.0
standard
No
A 10-aa standard natural tumor-homing peptides peptide sequence curated from TumorHoPe2.0, with an available 3D structural model.
N-terminal: cysteine/ maleimidohexanoic acid
Sequence
GACRGDCLGA
Physicochemical Analysis
C34H59N13O13S2
NEQHIKMFPSTWYV
G
922.04
5.95
1
1
3
-0
0.69
0.320
59.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
125
13.56
2
Residue Composition
number
2
A
1
R
0
N
1
D
2
C
0
E
0
Q
3
G
0
H
0
I
1
L
0
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 2 R: 1 N: 0 D: 1 C: 2 E: 0 Q: 0 G: 3 H: 0 I: 0 L: 1 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
10
C34H59N13O13S2
922.04
5.95
-0
0.69
0.320
cysteine/ maleimidohexanoic acid
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Tumor cell, Endothelial cell, Tumor vessel
Homing

Source & Reference

TumorHoPe2.0
TumorHoPe2
Increasing Tumor Accessibility with Conjugatable Disulfide-Bridged Tumor-Penetrating Peptides for Cancer Diagnosis and Treatment
2016
Venkata Ramana Kotamraju et al. Breast Cancer (Auckl). 2016 Jun 27 9(Suppl 2):79-87.

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
HeLa pLuc 705, MCF10Ca1A human breast cancer cells
Nude mice
Synthetic
FAM-Cys(oligonucleotide)
Additional Detail Fields 3 fields
FAM-Cys(oligonucleotide)
HeLa pLuc 705, MCF10Ca1A human breast cancer cells
Nude mice