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Peptide record

TPDB65776

FH Tumor-homing Peptides standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB65776
FH
Tumor-homing Peptides
Cancer-related peptides
TumorHoPe2.0
standard
No
A 12-aa standard natural tumor-homing peptides peptide sequence curated from TumorHoPe2.0, with an available 3D structural model.
Sequence
FHHPSIHDRHRH
Physicochemical Analysis
C69H98N28O16
ANCEQGLKMTWYV
H
1575.72
10.89
7
1
2
+1
6.79
-1.967
32.50
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
1
Residue Composition
number
0
A
2
R
0
N
1
D
0
C
0
E
0
Q
0
G
5
H
1
I
0
L
0
K
0
M
1
F
1
P
1
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 2 N: 0 D: 1 C: 0 E: 0 Q: 0 G: 0 H: 5 I: 1 L: 0 K: 0 M: 0 F: 1 P: 1 S: 1 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
12
C69H98N28O16
1575.72
10.89
+1
6.79
-1.967
SFEDRHWHHN
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Tumor cell
Homing
Breast cancer
Four-and-a-half LIM-only protein 3 (FHL3)

Source & Reference

TumorHoPe2.0
TumorHoPe2
Selectively Suppressing Tumor Angiogenesis for Targeted Breast Cancer Therapy by Genetically Engineered Phage
2020
Li Y et al. Adv Mater. 2020 Jul 32(29):e2001260

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
Nude mice bearing human MCF-7 breast tumors
Phage Display Library
Alexa Fluor
Additional Detail Fields 2 fields
Alexa Fluor
Nude mice bearing human MCF-7 breast tumors