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Peptide record

TPDB65774

Tumor-homing Peptides standard
4 amino acids
Basic Information
3D PDB MODEL
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TPDB65774
Tumor-homing Peptides
Cancer-related peptides
TumorHoPe2.0
standard
No
A 4-aa standard natural tumor-homing peptides peptide sequence curated from TumorHoPe2.0, with an available 3D structural model.
C-terminal: PEG2k-LPEI N-terminal: NH—(CH2)7—CO)
Sequence
FFDC
Physicochemical Analysis
C25H30N4O7S1
ARNEQGHILKMPSTWYV
F
530.60
3.10
0
1
2
-1
-1.27
1.150
0.00
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
1
Residue Composition
number
0
A
0
R
0
N
1
D
1
C
0
E
0
Q
0
G
0
H
0
I
0
L
0
K
0
M
2
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 1 C: 1 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 0 M: 0 F: 2 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
4
C25H30N4O7S1
530.60
3.10
-1
-1.27
1.150
PEG2k-LPEI
NH—(CH2)7—CO)
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Tumor cell
Targeting
Breast cancer
EGFR

Source & Reference

TumorHoPe2.0
TumorHoPe2
Method of treating cancer
2022
US 11298376 B2
US 11298376 B2

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
Breast cancer cell line (MDA-MB-231, BT474)
female nude mice 5 weeks old
Synthetic(Chemically modified)
PEG moieties, LPEI
At 3rd position (NH—CH2—CH(NH2)—CO)
Additional Detail Fields 3 fields
PEG moieties, LPEI
Breast cancer cell line (MDA-MB-231, BT474)
female nude mice 5 weeks old