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Peptide record

TPDB65772

Tumor-homing Peptides standard
15 amino acids
Basic Information
3D PDB MODEL
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TPDB65772
Tumor-homing Peptides
Cancer-related peptides
TumorHoPe2.0
standard
No
A 15-aa standard natural tumor-homing peptides peptide sequence curated from TumorHoPe2.0, with an available 3D structural model.
Sequence
FCDGFYACYADVGGG
Physicochemical Analysis
C69H89N15O22S2
RNEQHILKMPSTW
G
1544.67
2.92
0
2
7
-2
-2.39
0.480
32.67
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
3105
201.01
4
Residue Composition
number
2
A
0
R
0
N
2
D
2
C
0
E
0
Q
4
G
0
H
0
I
0
L
0
K
0
M
2
F
0
P
0
S
0
T
0
W
2
Y
1
V
Amino Acid Distribution
A: 2 R: 0 N: 0 D: 2 C: 2 E: 0 Q: 0 G: 4 H: 0 I: 0 L: 0 K: 0 M: 0 F: 2 P: 0 S: 0 T: 0 W: 0 Y: 2 V: 1
Chemical Descriptors
15
C69H89N15O22S2
1544.67
2.92
-2
-2.39
0.480
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Tumor cell
Targeting
Breast cancer
Her-2

Source & Reference

TumorHoPe2.0
TumorHoPe2
Improved drug delivery and therapeutic efficacy of PEgylated liposomal doxorubicin by targeting anti-HER2 peptide in murine breast tumor model
2016
Zahmatkeshana M et al. Eur J Pharm Sci. 2016 Apr 30:86:125-35

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
SK-BR-3, TUBO, MDA-MB-231
4-6 Week old Female Balb/c mice
Synthetic
Doxorubicin
Additional Detail Fields 3 fields
Doxorubicin
SK-BR-3, TUBO, MDA-MB-231
4-6 Week old Female Balb/c mice