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Peptide record

TPDB65768

Tumor-homing Peptides standard
10 amino acids
Basic Information
3D PDB MODEL
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TPDB65768
Tumor-homing Peptides
Cancer-related peptides
TumorHoPe2.0
standard
No
A 10-aa standard natural tumor-homing peptides peptide sequence curated from TumorHoPe2.0, with an available 3D structural model.
Sequence
EPYSTCGYSQ
Physicochemical Analysis
C48H67N11O19S1
ARNDHILKMFWV
SY
1134.18
3.29
0
1
2
-1
1.34
-1.140
0.00
Mammalian: 1 hour Yeast: 30 min E.coli: >10 hour
2980
262.74
7
Residue Composition
number
0
A
0
R
0
N
0
D
1
C
1
E
1
Q
1
G
0
H
0
I
0
L
0
K
0
M
0
F
1
P
2
S
1
T
0
W
2
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 1 E: 1 Q: 1 G: 1 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 1 S: 2 T: 1 W: 0 Y: 2 V: 0
Chemical Descriptors
10
C48H67N11O19S1
1134.18
3.29
-1
1.34
-1.140
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Endothelial vessel
Targeting
Glioblastoma
MAM, Ig domain, FNIII repeats

Source & Reference

TumorHoPe2.0
TumorHoPe2
Compositions and methods for treating cancer
2020
US 10745703 B2
US 10745703 B2

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
Human Glioblastoma Cell line LN-229, Gli36Δ5 human glioma cell line
NIH athymic nude female mice
Synthetic
nanoparticle
Additional Detail Fields 3 fields
nanoparticle
Human Glioblastoma Cell line LN-229, Gli36Δ5 human glioma cell line
NIH athymic nude female mice