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Peptide record

TPDB65763

Tumor-homing Peptides modified_plain modified
11 amino acids
Basic Information
3D PDB MODEL
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TPDB65763
Tumor-homing Peptides
Cancer-related peptides
TumorHoPe2.0
modified_plain
Yes
A 11-aa modified tumor-homing peptides peptide sequence curated from TumorHoPe2.0, with an available 3D structural model.
Modified, details unspecified
Sequence
DNRIRLQAKXX
Physicochemical Analysis
C46H84N18O14
CEGHMFPSTWYV
R
1113.29
11.32
3
1
3
+2
3.80
-1.209
80.00
Mammalian: 1.1 hour Yeast: 3 min E.coli: >10 hour
0
0.00
2
Residue Composition
number
1
A
2
R
1
N
1
D
0
C
0
E
1
Q
0
G
0
H
1
I
1
L
1
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 2 N: 1 D: 1 C: 0 E: 0 Q: 1 G: 0 H: 0 I: 1 L: 1 K: 1 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
11
C46H84N18O14
1113.29
11.32
+2
3.80
-1.209
Evidence Records 2 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Tumor cell
Targeting
Prostate cancer

Source & Reference

TumorHoPe2.0
TumorHoPe2
Compositions of a peptide targeting system for treating cancer
2014
US 8680045 B2
US 8680045 B2

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
LNCaP, PC3
Nude mice (20 g)
Phage display library
Cy5.5
Evidence 2 Activity

Activity

Tumor-homing Peptides

Target

Tumor cell
Targeting
Prostate cancer
Alpha-6-beta 1

Source & Reference

TumorHoPe2.0
TumorHoPe2
Protease inhibitor:protease sensitive expression system, composition and methods for improving the therapeutic activity and specificity of proteins delivered by bacteria
2022
US 11219671 B1
US 11219671 B1

Other

DU145 prostate cancer cell line
Salmonella typhimurium
Phage display library
Ph.D-7 Phage Display
Additional Detail Fields 4 fields
Cy5.5
LNCaP, PC3 DU145 prostate cancer cell line
Nude mice (20 g) Salmonella typhimurium
Ph.D-7 Phage Display