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Peptide record

TPDB65760

Tumor-homing Peptides standard
5 amino acids
Basic Information
3D PDB MODEL
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TPDB65760
Tumor-homing Peptides
Cancer-related peptides
TumorHoPe2.0
standard
No
A 5-aa standard natural tumor-homing peptides peptide sequence curated from TumorHoPe2.0, with an available 3D structural model.
Sequence
DFKRG
Physicochemical Analysis
C27H43N9O8
ANCEQHILMPSTWYV
RDGKF
621.69
10.09
2
1
1
+1
1.91
-1.900
0.00
Mammalian: 1.1 hour Yeast: 3 min E.coli: >10 hour
0
0.00
0
Residue Composition
number
0
A
1
R
0
N
1
D
0
C
0
E
0
Q
1
G
0
H
0
I
0
L
1
K
0
M
1
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 1 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 0 L: 0 K: 1 M: 0 F: 1 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
5
C27H43N9O8
621.69
10.09
+1
1.91
-1.900
RGD
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Tumor cell
Targeting
Breast cancer
Alpha-5 beta -3 integrins

Source & Reference

TumorHoPe2.0
TumorHoPe2
Tumor-targeted/reduction-triggered composite multifunctional nanoparticles for breast cancer chemo-photothermal combinational therapy
2022
Yang Y et al. Acta Pharm Sin B. 2022 Jun 12(6):2710-2730

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
4T1 cell
5-6 weeks old female BALB/c mice
Synthetic
Amphiphilic block copolymers (COOH- PEG4000-PssCPT9)
cyclo
Additional Detail Fields 3 fields
Amphiphilic block copolymers (COOH- PEG4000-PssCPT9)
4T1 cell
5-6 weeks old female BALB/c mice