Back to search

Peptide record

TPDB65759

Tumor-homing Peptides standard
8 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB65759
Tumor-homing Peptides
Cancer-related peptides
TumorHoPe2.0
standard
No
A 8-aa standard natural tumor-homing peptides peptide sequence curated from TumorHoPe2.0, with an available 3D structural model.
Sequence
DFKLFAVY
Physicochemical Analysis
C51H71N9O12
RNCEQGHIMPSTW
F
1002.18
6.68
1
1
6
-0
-1.64
0.838
97.50
Mammalian: 1.1 hour Yeast: 3 min E.coli: >10 hour
1490
148.68
1
Residue Composition
number
1
A
0
R
0
N
1
D
0
C
0
E
0
Q
0
G
0
H
0
I
1
L
1
K
0
M
2
F
0
P
0
S
0
T
0
W
1
Y
1
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 1 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 1 K: 1 M: 0 F: 2 P: 0 S: 0 T: 0 W: 0 Y: 1 V: 1
Chemical Descriptors
8
C51H71N9O12
1002.18
6.68
-0
-1.64
0.838
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Tumor cell
Homing
Breast cancer, Squamous cell carcinoma, Colon carcinoma
vimentin

Source & Reference

TumorHoPe2.0
TumorHoPe2
Carcinoma homing peptide (CHP), its analogs, and methods of using
2017
US 9657077 B2
US 9657077 B2

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
SCCVII, CT26, 4T1, and B16F10 cell line
C57B1/6 mice, C3H mice, Nude mice, wtIL-12−/− mice, female Balb/c mice (all are six to eight weeks old)
Phage Display library
interleukin 12 (IL-12)
Additional Detail Fields 3 fields
interleukin 12 (IL-12)
SCCVII, CT26, 4T1, and B16F10 cell line
C57B1/6 mice, C3H mice, Nude mice, wtIL-12−/− mice, female Balb/c mice (all are six to eight weeks old)