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Peptide record

TPDB65758

NGR Tumor-homing Peptides standard
8 amino acids
Basic Information
3D PDB MODEL
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TPDB65758
NGR
Tumor-homing Peptides
Cancer-related peptides
TumorHoPe2.0
standard
No
A 8-aa standard natural tumor-homing peptides peptide sequence curated from TumorHoPe2.0, with an available 3D structural model.
N-terminal: Cysteine
Sequence
CYGGRGNG
Physicochemical Analysis
C30H46N12O11S1
ADEQHILKMFPSTWV
G
782.83
8.91
1
0
1
+1
0.09
-1.050
0.00
Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour
1490
190.34
3
Residue Composition
number
0
A
1
R
1
N
0
D
1
C
0
E
0
Q
4
G
0
H
0
I
0
L
0
K
0
M
0
F
0
P
0
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 1 N: 1 D: 0 C: 1 E: 0 Q: 0 G: 4 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
8
C30H46N12O11S1
782.83
8.91
+1
0.09
-1.050
Cysteine
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Tumor cell
Targeting
Glioma
CD13

Source & Reference

TumorHoPe2.0
TumorHoPe2
Dual-Modified Novel Biomimetic Nanocarriers Improve Targeting and Therapeutic Efficacy in Glioma
2019
Fu S et al. ACS Appl Mater Interfaces. 2019 Jan 16 11(2):1841-1854

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
Human umbilical vein endothelial cells (HUVECs)
Male and Female ICR mice
Synthetic
DSPE- PEG2000-Mal
Additional Detail Fields 3 fields
DSPE- PEG2000-Mal
Human umbilical vein endothelial cells (HUVECs)
Male and Female ICR mice