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Peptide record

TPDB65736

Tumor-homing Peptides standard
10 amino acids
Basic Information
3D PDB MODEL
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TPDB65736
Tumor-homing Peptides
Cancer-related peptides
TumorHoPe2.0
standard
No
A 10-aa standard natural tumor-homing peptides peptide sequence curated from TumorHoPe2.0, with an available 3D structural model.
Sequence
CSWKYWFGEC
Physicochemical Analysis
C62H77N13O15S2
ARNDQHILMPTV
CW
1308.49
6.13
1
1
4
-0
-3.10
-0.390
0.00
Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour
12615
964.09
4
Residue Composition
number
0
A
0
R
0
N
0
D
2
C
1
E
0
Q
1
G
0
H
0
I
0
L
1
K
0
M
1
F
0
P
1
S
0
T
2
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 2 E: 1 Q: 0 G: 1 H: 0 I: 0 L: 0 K: 1 M: 0 F: 1 P: 0 S: 1 T: 0 W: 2 Y: 1 V: 0
Chemical Descriptors
10
C62H77N13O15S2
1308.49
6.13
-0
-3.10
-0.390
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Tumor cell, Endothelial cell, Tumor vessel
Homing

Source & Reference

TumorHoPe2.0
TumorHoPe2
Targeted Proapoptotic Peptides Depleting Adipose Stromal Cells Inhibit Tumor Growth
2016
Alexes C Daquinag et al. Mol Ther. 2016 Feb 24(1):34-40.

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
B16F10, LLC, E0771, 4T1.2 cell line
C57BL/6, BALB/c, C57BL/6-Tg(UBC-GFP)30Scha/J (GFP mice), B6.Cg-Tg(ACTB-mRFP1)1F1Hadj/J (RFP mice), C57BL/6-Tg(Pdgfra-cre)1Clc
Synthetic
Alexa 488, streptavidin, Cy3
Cyclic
Additional Detail Fields 3 fields
Alexa 488, streptavidin, Cy3
B16F10, LLC, E0771, 4T1.2 cell line
C57BL/6, BALB/c, C57BL/6-Tg(UBC-GFP)30Scha/J (GFP mice), B6.Cg-Tg(ACTB-mRFP1)1F1Hadj/J (RFP mice), C57BL/6-Tg(Pdgfra-cre)1Clc