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Peptide record

TPDB65733

UNO Tumor-homing Peptides standard
9 amino acids
Basic Information
3D PDB MODEL
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TPDB65733
UNO
Tumor-homing Peptides
Cancer-related peptides
TumorHoPe2.0
standard
No
A 9-aa standard natural tumor-homing peptides peptide sequence curated from TumorHoPe2.0, with an available 3D structural model.
Sequence
CSPGAKVRC
Physicochemical Analysis
C36H65N13O11S2
NDEQHILMFTWY
C
920.11
9.15
2
0
2
+2
1.81
-0.022
43.33
Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour
125
13.59
3
Residue Composition
number
1
A
1
R
0
N
0
D
2
C
0
E
0
Q
1
G
0
H
0
I
0
L
1
K
0
M
0
F
1
P
1
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 1 R: 1 N: 0 D: 0 C: 2 E: 0 Q: 0 G: 1 H: 0 I: 0 L: 0 K: 1 M: 0 F: 0 P: 1 S: 1 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
9
C36H65N13O11S2
920.11
9.15
+2
1.81
-0.022
CSPGAK
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Macrophage, Tumor cell, Endothelial cell
Homing
Breast cancer, Glioblastoma, Melanoma, Gastric carcinoma
CD206 (Mannose receptor)

Source & Reference

TumorHoPe2.0
TumorHoPe2
Precision Targeting of Tumor Macrophages with a CD206 Binding Peptide
2017
Pablo Scodeller et al. Sci Rep. 2017 Nov 7 7(1):14655.

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
gastric carcinoma cell line MKN4-5P, B16F10 melanoma cells
8-week old female Balb/c mice, 8-week old female nude mice, C57BL6 mice
Phage Display Library
FAM-UNO, Paclitaxel-loaded nanoparticles
Additional Detail Fields 3 fields
FAM-UNO, Paclitaxel-loaded nanoparticles
gastric carcinoma cell line MKN4-5P, B16F10 melanoma cells
8-week old female Balb/c mice, 8-week old female nude mice, C57BL6 mice