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Peptide record

TPDB65715

Tumor-homing Peptides standard
6 amino acids
Basic Information
3D PDB MODEL
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TPDB65715
Tumor-homing Peptides
Cancer-related peptides
TumorHoPe2.0
standard
No
A 6-aa standard natural tumor-homing peptides peptide sequence curated from TumorHoPe2.0, with an available 3D structural model.
Sequence
CRGDYK
Physicochemical Analysis
C30H48N10O10S1
ANEQHILMFPSTWV
RDCGKY
740.83
8.88
2
1
1
+1
1.86
-1.850
0.00
Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour
1490
201.13
2
Residue Composition
number
0
A
1
R
0
N
1
D
1
C
0
E
0
Q
1
G
0
H
0
I
0
L
1
K
0
M
0
F
0
P
0
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 1 C: 1 E: 0 Q: 0 G: 1 H: 0 I: 0 L: 0 K: 1 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
6
C30H48N10O10S1
740.83
8.88
+1
1.86
-1.850
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Targeting
Skin cancer
Alpha-5 beta -3 integrins, Thermosensitive liposomes(TSLs)

Source & Reference

TumorHoPe2.0
TumorHoPe2
Dual-modal imaging-guided theranostic nanocarriers based on 2-methoxyestradiol and indocyanine green
2021
Zhang N et al. Int J Pharm. 2021 Jan 5:592:120098

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
B16-F10 murine melanoma cancer cell line
6-8 weeks old female Balb/c mice
Synthetic
FITC
Additional Detail Fields 3 fields
FITC
B16-F10 murine melanoma cancer cell line
6-8 weeks old female Balb/c mice