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Peptide record

TPDB65706

CREKA Tumor-homing Peptides standard
16 amino acids
Basic Information
3D PDB MODEL
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TPDB65706
CREKA
Tumor-homing Peptides
Cancer-related peptides
TumorHoPe2.0
standard
No
A 16-aa standard natural tumor-homing peptides peptide sequence curated from TumorHoPe2.0, with an available 3D structural model.
C-terminal: Amidation
Sequence
CREKAKKLFKKILKFL-NH2
Physicochemical Analysis
C95H165N25O19S1
NDQGHMPSTWYV
K
1993.57
10.82
7
1
7
+6
4.11
-0.350
103.75
Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
1
Residue Composition
number
1
A
1
R
0
N
0
D
1
C
1
E
0
Q
0
G
0
H
1
I
3
L
6
K
0
M
2
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 1 N: 0 D: 0 C: 1 E: 1 Q: 0 G: 0 H: 0 I: 1 L: 3 K: 6 M: 0 F: 2 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
16
C95H165N25O19S1
1993.57
10.82
+6
4.11
-0.350
Amide
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Tumor vessel
Homing
Breast cancer

Source & Reference

TumorHoPe2.0
TumorHoPe2
Identification of BP16 as a non-toxic cell-penetrating peptide with highly efficient drug delivery properties
2014
Marta Soler et al. Org Biomol Chem. 2014 Mar 14, 12, 1652-1663

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
breast adenocarcinoma MCF-7, pancreas adenocarcinoma CAPAN-1, mouse embryonic fibroblast 3T3 cell line
Phage display library
CECMEL11 peptide library
BP76 ( KKLFKKILKFL)
Additional Detail Fields 3 fields
BP76 ( KKLFKKILKFL)
breast adenocarcinoma MCF-7, pancreas adenocarcinoma CAPAN-1, mouse embryonic fibroblast 3T3 cell line
CECMEL11 peptide library