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Peptide record

TPDB65702

Tumor-homing Peptides standard
10 amino acids
Basic Information
3D PDB MODEL
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TPDB65702
Tumor-homing Peptides
Cancer-related peptides
TumorHoPe2.0
standard
No
A 10-aa standard natural tumor-homing peptides peptide sequence curated from TumorHoPe2.0, with an available 3D structural model.
Sequence
CRDLNGRKVM
Physicochemical Analysis
C47H86N18O14S2
AEQHIFPSTWY
R
1191.43
10.10
3
1
3
+2
3.31
-0.790
68.00
Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
2
Residue Composition
number
0
A
2
R
1
N
1
D
1
C
0
E
0
Q
1
G
0
H
0
I
1
L
1
K
1
M
0
F
0
P
0
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 2 N: 1 D: 1 C: 1 E: 0 Q: 0 G: 1 H: 0 I: 0 L: 1 K: 1 M: 1 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
10
C47H86N18O14S2
1191.43
10.10
+2
3.31
-0.790
NGR
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Tumor cell, Tumor vessel, Tumor stem cell, Endothelial cell, Epithelial cell, Dendritic cell
Homing

Source & Reference

TumorHoPe2.0
TumorHoPe2
Methods and compositions using peptides and proteins with C-terminal elements
2019
US 10370245 B2
US 10370245 B2

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
PPC-1, PC-3, Du-145, 4T1, MIA PaCa-2, PDAC1.3, B16F10, M21, and MDA-MB-435 cell line
BALB/c athymic nude mice
Phage Display library
T7 phage display library
nanoparticles, nanoworms, 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[maleimide(polyethylene glycol)2000 DSPE-PEG2000-maleimide]
Additional Detail Fields 4 fields
nanoparticles, nanoworms, 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[maleimide(polyethylene glycol)2000 DSPE-PEG2000-maleimide]
PPC-1, PC-3, Du-145, 4T1, MIA PaCa-2, PDAC1.3, B16F10, M21, and MDA-MB-435 cell line
BALB/c athymic nude mice
T7 phage display library