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Peptide record

TPDB65689

Tumor-homing Peptides standard
9 amino acids
Basic Information
3D PDB MODEL
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TPDB65689
Tumor-homing Peptides
Cancer-related peptides
TumorHoPe2.0
standard
No
A 9-aa standard natural tumor-homing peptides peptide sequence curated from TumorHoPe2.0, with an available 3D structural model.
Sequence
CNWMINKEC
Physicochemical Analysis
C47H73N13O14S3
ARDQGHLFPSTYV
NC
1140.36
6.14
1
1
3
-0
0.98
-0.433
43.33
Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour
5625
493.27
4
Residue Composition
number
0
A
0
R
2
N
0
D
2
C
1
E
0
Q
0
G
0
H
1
I
0
L
1
K
1
M
0
F
0
P
0
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 2 D: 0 C: 2 E: 1 Q: 0 G: 0 H: 0 I: 1 L: 0 K: 1 M: 1 F: 0 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
9
C47H73N13O14S3
1140.36
6.14
-0
0.98
-0.433
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Homing
Renal Cell carcinoma(RCC), Ovarian clear cell carcinoma
KIM-1(Kidney injury molecule-1)

Source & Reference

TumorHoPe2.0
TumorHoPe2
A Phage Display-Identified Peptide Selectively Binds to Kidney Injury Molecule-1 (KIM-1) and Detects KIM-1-Overexpressing Tumors in vivo
2018
Enamul Haque M et al. Cancer Res Treat. 2019 Jul 51(3):861-875.

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
769-P, A549, ACHN, A498, HepG2, HEK-293 cells
6-week-old BALB/c nu/nu female mice
Phage display library
M13 phage
FITC
Additional Detail Fields 4 fields
FITC
769-P, A549, ACHN, A498, HepG2, HEK-293 cells
6-week-old BALB/c nu/nu female mice
M13 phage