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Peptide record

TPDB65685

Tumor-homing Peptides standard
10 amino acids
Basic Information
3D PDB MODEL
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TPDB65685
Tumor-homing Peptides
Cancer-related peptides
TumorHoPe2.0
standard
No
A 10-aa standard natural tumor-homing peptides peptide sequence curated from TumorHoPe2.0, with an available 3D structural model.
Sequence
CNGRCKHKHK
Physicochemical Analysis
C48H83N21O12S2
ADEQILMFPSTWYV
K
1210.44
10.32
6
0
0
+4
5.65
-2.150
0.00
Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour
125
10.33
3
Residue Composition
number
0
A
1
R
1
N
0
D
2
C
0
E
0
Q
1
G
2
H
0
I
0
L
3
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 1 N: 1 D: 0 C: 2 E: 0 Q: 0 G: 1 H: 2 I: 0 L: 0 K: 3 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
10
C48H83N21O12S2
1210.44
10.32
+4
5.65
-2.150
NGR
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Tumor cell
Targeting
Breast cancer
Aminopeptidase N (CD13)

Source & Reference

TumorHoPe2.0
TumorHoPe2
NIR-/pH-Responsive drug delivery of functionalized single-walled carbon nanotubes for potential application in cancer chemo-photothermal therapy
2013
Lei Wang et al. Pharm Res. 2013 Nov 30(11):2757-71.

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
MCF-7 human breast cancer cell line
Female BALB/c nude mice (4-6 weeks old)
Synthetic
SWNT-PEI, Doxorubicin (DOX)
Additional Detail Fields 3 fields
SWNT-PEI, Doxorubicin (DOX)
MCF-7 human breast cancer cell line
Female BALB/c nude mice (4-6 weeks old)