Back to search

Peptide record

TPDB65684

NEW Tumor-homing Peptides standard
9 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB65684
NEW
Tumor-homing Peptides
Cancer-related peptides
TumorHoPe2.0
standard
No
A 9-aa standard natural tumor-homing peptides peptide sequence curated from TumorHoPe2.0, with an available 3D structural model.
N-terminal: Biotinylation
Sequence
CNEWQLKSC
Physicochemical Analysis
C46H71N13O15S2
ARDGHIMFPTYV
C
1110.27
6.14
1
1
2
-0
1.25
-0.811
43.33
Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour
5625
506.63
5
Residue Composition
number
0
A
0
R
1
N
0
D
2
C
1
E
1
Q
0
G
0
H
0
I
1
L
1
K
0
M
0
F
0
P
1
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 1 D: 0 C: 2 E: 1 Q: 1 G: 0 H: 0 I: 0 L: 1 K: 1 M: 0 F: 0 P: 0 S: 1 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
9
C46H71N13O15S2
1110.27
6.14
-0
1.25
-0.811
Biotinylation
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Tumor cell
Homing
tumor metastasis
CD44v6

Source & Reference

TumorHoPe2.0
TumorHoPe2
Identification of novel CD44v6-binding peptides that block CD44v6 and deliver a pro-apoptotic peptide to tumors to inhibit tumor growth and metastasis in mice
2021
Khan F et al. Theranostics. 2021 Jan 1 11(3):1326-1344.

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
HEK 293T, MDA-MB231, MCF-7, 4T1, Panc-2
6-week-old female BALB/c nude mouse
Phage display library
T7 phage / CX7C peptide library
FITC, TAMRA, Flamma 675 near-infrared (NIR) fluorescence dye
Additional Detail Fields 4 fields
FITC, TAMRA, Flamma 675 near-infrared (NIR) fluorescence dye
HEK 293T, MDA-MB231, MCF-7, 4T1, Panc-2
6-week-old female BALB/c nude mouse
T7 phage / CX7C peptide library